Hemeteam has six parts.

1: Common problems
2: Case Studies
3: Hematopoiesis
4: Diseases of blood formation
5: Bleeding and clotting
6: Targeted therapy

Welcome to HemeTeam 2010

Basic concepts in hematology: pathophysiology, diagnosis and treatment.

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Contents

Part 1. Common problems

• Diagnosis of anemia
• Anemia of chronic disease
• Blood and marrow smears
• Abnormal leukocyte counts
• Approach to abnormal platelet counts
• Lymphadenopathy
• approach  to splenomegaly
• Bleeding
• Venous thromboembolism (VTE)
• Acute leukemia (an introduction) 

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Part 2. Case studies

• microcytic anemia in a marathon runner
• anemia in a patient with a chronic disease (ACD)
• anemia in a greek woman
• unexplained macrocytosis
• fatigue and bruising in an auto mechanic
• pancytopenia post influenza
• ALL in a male aged 3 in 1966
• AML: 5 case studies
• APL in a Jehovah's witness
• Thymic mass in an infant
• Hodgkin's disease in a young boy
• Peripheral T - cell lymphoma- 5 cases
• Vignettes- complications of polycythemia vera
• Polycythemia and ascites
• Splenomegaly in a 76 year old lawyer

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Part 3. Hematopoiesis

• Overview of Hematopoiesis
• cell cycle 
• stem cells
• telomerase
• apoptosis
• angiogenesis
• endothelium
• granulopoiesis
• thrombopoiesis
• lymphopoiesis
• aplastic anemia  and pancytopenia

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Part 4. Diseases of Blood Formation:

a) Erythrocytes

• Diagnosis of different types of anemia
• microcytic
• macrocytic
• normocytic
• hemolytic
• anemia of chronic disease
• sickle cell disease
• iron deficiency, absorption, transport etc
• hemochromatosis

b) Stem cells

• acute myelogenous leukemia (AML)
• acute promyelocytic leukemia (APL)
• prognostic Factors in AML
• biology of acute myeloid leukemia (AML)
• minimal residual disease (MRD)
• multidrug resistance (MDR)
• stem cell transplantation (SCT) in AML
• chronic myelogenous leukemia (CML)
• biology of CML
• inatinib mesylate (targeted Rx for CML
• myeloproliferative disorders (MPD)
• polycythemia rubra vera (PRV)
• essential thrombocytosis (ET)
• myelofibrosis with myeloid metaplasia (MMM)
• myelodysplastic syndromes (MDS)

c) Lymphocytes

• Lymphopoiesis
• approach to lymphadenopathy
• approach  to splenomegaly
• acute lymphocytic leukemia (ALL)
• chronic lymphocytic leukemia (CLL)
• biology of CLL
• Hodgkin's disease
• non-Hodgkin lymphoma (NHL)
• follicular cell lymphoma (FCL)
• peripheral T-cell lymphoma (PTCL)
• multiple myeloma
• amyloidosis

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Part 5. Bleeding and Clotting

• Approach to abnormal Bleeding
• Platelets in Health and disease
• Thrombocytopenia
• Von Willebrand's disease
• Thrombophilia and venous thromboembolism
• Anti-phospholipid antibody syndrome
• Heparin induced thrombocytopenia (HIT)
• Thrombotic thrombocytopenic purpura (TTP)

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Part 6. Targeted Therapy

• targeted therapy of CML
• antisense oligonucleotides  (anti BCL-2)
• thalidomide and Lenalidomide
• rituximab (anti CD20)
• targeted therapy of AML
• epigenetic therapies
• vascular endothelial growth factor (VEGF)
• Personalized therapy
• Proteins
• Proteomics
• MicroRNAs

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You may freely use The  QxMD Hematology Calculator which has many interesting uses.